Laboratory of Cytogenetic and Molecular Diagnostics

Main equipment:
- Agilent Technologies hybridization oven for aCGH studies
- CytoHyb CT500 incubator Smartgene Hybridization plate FISH
- Thermobrite Stat-Spin Hybridization Plate for FISH
- NanoDrop ND l OOO spectrophotometer for measuring the concentration of nucleic acids
- Maxwell CSC - nucleic acid isolation
- MiSeq Illumina Sequencer
- Ultrasound DNA fragmentator

Scope of services:
- Short-term cultivation of cell lines derived from lymphocytes, amniocytes, bone marrow cells and cells from neoplastic tissues and other human cells
- Diagnostics of metaphasal chromosomes stained with GTW technique
- Diagnostics of selected chromosomal aberrations / rearrangements using the FISH technique on both metaphages and interphasal nuclei, on the material after cell culture and FFPE tissues.
- Diagnosis of genome imbalances using the microarray technique (aCGH).
- Nucleic acids isolation from various types of biological material.
- Molecular studies with the use of molecular biology techniques, i.e. next-generation sequencing (NGS) and direct sequencing using the Sanger method, MLPA, qPCR, HRM.